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Aldosterone induces albuminuria via matrix metalloproteinase-dependent damage of the endothelial glycocalyx
Aldosterone contributes to end-organ damage in heart failure and chronic kidney disease. Mineralocorticoid-receptor inhibitors limit activation of the receptor by aldosterone and slow disease progression, but side effects, including hyperkalemia, limit their clinical use. Damage to the endothelial g...
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| 出版年: | Kidney Int |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6506575/ https://ncbi.nlm.nih.gov/pubmed/30389198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2018.08.024 |
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