Vascular Endothelial Growth Factor-A(165)b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy

Diabetic nephropathy is the leading cause of ESRD in high-income countries and a growing problem across the world. Vascular endothelial growth factor-A (VEGF-A) is thought to be a critical mediator of vascular dysfunction in diabetic nephropathy, yet VEGF-A knockout and overexpression of angiogenic...

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Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Oltean, Sebastian, Qiu, Yan, Ferguson, Joanne K., Stevens, Megan, Neal, Chris, Russell, Amy, Kaura, Amit, Arkill, Kenton P., Harris, Kirstie, Symonds, Clare, Lacey, Katja, Wijeyaratne, Lihini, Gammons, Melissa, Wylie, Emma, Hulse, Richard P., Alsop, Chloe, Cope, George, Damodaran, Gopinath, Betteridge, Kai B., Ramnath, Raina, Satchell, Simon C., Foster, Rebecca R., Ballmer-Hofer, Kurt, Donaldson, Lucy F., Barratt, Jonathan, Baelde, Hans J., Harper, Steven J., Bates, David O., Salmon, Andrew H.J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2015
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520162/
https://ncbi.nlm.nih.gov/pubmed/25542969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014040350
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