Vascular Endothelial Growth Factor-A(165)b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy

Diabetic nephropathy is the leading cause of ESRD in high-income countries and a growing problem across the world. Vascular endothelial growth factor-A (VEGF-A) is thought to be a critical mediator of vascular dysfunction in diabetic nephropathy, yet VEGF-A knockout and overexpression of angiogenic...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Oltean, Sebastian, Qiu, Yan, Ferguson, Joanne K., Stevens, Megan, Neal, Chris, Russell, Amy, Kaura, Amit, Arkill, Kenton P., Harris, Kirstie, Symonds, Clare, Lacey, Katja, Wijeyaratne, Lihini, Gammons, Melissa, Wylie, Emma, Hulse, Richard P., Alsop, Chloe, Cope, George, Damodaran, Gopinath, Betteridge, Kai B., Ramnath, Raina, Satchell, Simon C., Foster, Rebecca R., Ballmer-Hofer, Kurt, Donaldson, Lucy F., Barratt, Jonathan, Baelde, Hans J., Harper, Steven J., Bates, David O., Salmon, Andrew H.J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2015
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520162/
https://ncbi.nlm.nih.gov/pubmed/25542969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014040350
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