Vascular Endothelial Growth Factor-A(165)b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy

Diabetic nephropathy is the leading cause of ESRD in high-income countries and a growing problem across the world. Vascular endothelial growth factor-A (VEGF-A) is thought to be a critical mediator of vascular dysfunction in diabetic nephropathy, yet VEGF-A knockout and overexpression of angiogenic...

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Bibliographic Details
Published in:J Am Soc Nephrol
Main Authors: Oltean, Sebastian, Qiu, Yan, Ferguson, Joanne K., Stevens, Megan, Neal, Chris, Russell, Amy, Kaura, Amit, Arkill, Kenton P., Harris, Kirstie, Symonds, Clare, Lacey, Katja, Wijeyaratne, Lihini, Gammons, Melissa, Wylie, Emma, Hulse, Richard P., Alsop, Chloe, Cope, George, Damodaran, Gopinath, Betteridge, Kai B., Ramnath, Raina, Satchell, Simon C., Foster, Rebecca R., Ballmer-Hofer, Kurt, Donaldson, Lucy F., Barratt, Jonathan, Baelde, Hans J., Harper, Steven J., Bates, David O., Salmon, Andrew H.J.
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2015
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520162/
https://ncbi.nlm.nih.gov/pubmed/25542969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014040350
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