Targeting the Fanconi Anemia/BRCA Pathway Circumvents Drug Resistance in Multiple Myeloma

The Fanconi Anemia (FA)/BRCA DNA damage repair pathway plays a pivotal role in the cellular response to replicative stress induced by DNA alkylating agents and greatly influences drug response in cancer treatment. We recently reported that FA/BRCA genes are overexpressed and causative for drug resis...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Yarde, Danielle N., Oliveira, Vasco, Mathews, Linda, Wang, Xingyu, Villagra, Alejandro, Boulware, David, Shain, Kenneth H., Hazlehurst, Lori A., Alsina, Melissa, Chen, Dung-Tsa, Beg, Amer A., Dalton, William S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519834/
https://ncbi.nlm.nih.gov/pubmed/19934314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2616
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