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β1 integrin adhesion enhances IL-6 mediated STAT3 signaling in Myeloma cells: Implications for Microenvironment Influence on Tumor Survival and Proliferation

The bone marrow microenvironmental components interleukin (IL)-6 and fibronectin (FN) individually influence the proliferation and survival of Multiple Myeloma (MM) cells; however, in vivo these effectors most likely work together. We examined signaling events, cell cycle progression, and levels of...

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Detalhes bibliográficos
Main Authors: Shain, Kenneth H., Yarde, Danielle N., Meads, Mark B., Huang, Mei, Jove, Richard, Hazlehurst, Lori A., Dalton, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680075/
https://ncbi.nlm.nih.gov/pubmed/19155309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2419
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