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Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma

Multiple myeloma (MM) remains an incurable malignancy due, in part, to the influence of the bone marrow microenvironment on survival and drug response. Identification of microenvironment-specific survival signaling determinants is critical for the rational design of therapy and elimination of MM. Pr...

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Podrobná bibliografie
Vydáno v:	Oncogene
Hlavní autoři:	Meads, MB, Fang, B, Mathews, L, Gemmer, J, Nong, L, Rosado-Lopez, I, Nguyen, T, Ring, JE, Matsui, W, MacLeod, AR, Pachter, JA, Hazlehurst, LA, Koomen, JM, Shain, KH
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	2015
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4801703/ https://ncbi.nlm.nih.gov/pubmed/26387544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.334
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Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma

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