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Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma

Multiple myeloma (MM) remains an incurable malignancy due, in part, to the influence of the bone marrow microenvironment on survival and drug response. Identification of microenvironment-specific survival signaling determinants is critical for the rational design of therapy and elimination of MM. Pr...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Meads, MB, Fang, B, Mathews, L, Gemmer, J, Nong, L, Rosado-Lopez, I, Nguyen, T, Ring, JE, Matsui, W, MacLeod, AR, Pachter, JA, Hazlehurst, LA, Koomen, JM, Shain, KH
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801703/
https://ncbi.nlm.nih.gov/pubmed/26387544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.334
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