Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma

Multiple myeloma (MM) remains an incurable malignancy due, in part, to the influence of the bone marrow microenvironment on survival and drug response. Identification of microenvironment-specific survival signaling determinants is critical for the rational design of therapy and elimination of MM. Pr...

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Publicado en:Oncogene
Autores principales: Meads, MB, Fang, B, Mathews, L, Gemmer, J, Nong, L, Rosado-Lopez, I, Nguyen, T, Ring, JE, Matsui, W, MacLeod, AR, Pachter, JA, Hazlehurst, LA, Koomen, JM, Shain, KH
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801703/
https://ncbi.nlm.nih.gov/pubmed/26387544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.334
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