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Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

The maintenance of genome stability is critical for survival, and its failure is often associated with tumorigenesis. The Fanconi anemia (FA) pathway is essential for the repair of DNA interstrand cross-links (ICLs), and a germline defect in the pathway results in FA, a cancer predisposition syndrom...

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Autors principals: Kim, Hyungjin, D'Andrea, Alan D.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403008/
https://ncbi.nlm.nih.gov/pubmed/22751496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.195248.112
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