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Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas
Bcl11b is a transcription factor important for T cell development and also a tumor-suppressor gene that is hemizygously inactivated in ~10 % human T cell acute lymphoblastic leukemia (T-ALL) and several murine T-ALL models, including ATM(−/−) thymic lymphomas. Here we report that heterozygous loss o...
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| Publicado no: | J Hematol Oncol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4518599/ https://ncbi.nlm.nih.gov/pubmed/26219558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0191-8 |
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