A carregar...

Early B-cell Specific Inactivation of ATM Synergizes with Ectopic CyclinD1 Expression to Promote Pre-germinal center B-cell Lymphomas in Mice

Ataxia Telangiectasia Mutated (ATM) kinase is a master regulator of the DNA damage response. ATM is frequently inactivated in human B-cell non-Hodgkin Lymphomas (B-NHL), including ~50% of mantle cell lymphomas (MCLs) characterized by ectopic expression of CyclinD1. Here we report that early and robu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Yamamoto, Kenta, Lee, Brian J., Li, Chen, Dubois, Richard L., Hobeika, Elias, Bhagat, Govind, Zha, Shan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282516/
https://ncbi.nlm.nih.gov/pubmed/25676421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.41
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!