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Voltage-gated sodium channels and cancer: is excitability their primary role?
Voltage-gated sodium channels (Na(V)) are molecular characteristics of excitable cells. Their activation, triggered by membrane depolarization, generates transient sodium currents that initiate action potentials in neurons and muscle cells. Sodium currents were discovered by Hodgkin and Huxley using...
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| Publicat a: | Front Pharmacol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4518325/ https://ncbi.nlm.nih.gov/pubmed/26283962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00152 |
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