Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells

Voltage-gated sodium channels (Na(V)) are functionally expressed in highly metastatic cancer cells derived from nonexcitable epithelial tissues (breast, prostate, lung, and cervix). MDA-MB-231 breast cancer cells express functional sodium channel complexes, consisting of Na(V)1.5 and associated auxi...

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Detalhes bibliográficos
Main Authors: Gillet, Ludovic, Roger, Sébastien, Besson, Pierre, Lecaille, Fabien, Gore, Jacques, Bougnoux, Philippe, Lalmanach, Gilles, Le Guennec, Jean-Yves
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659227/
https://ncbi.nlm.nih.gov/pubmed/19176528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806891200
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