Atomic view of the histidine environment stabilizing higher-pH conformations of pH-dependent proteins

External stimuli are powerful tools that naturally control protein assemblies and functions. For example, during viral entry and exit changes in pH are known to trigger large protein conformational changes. However, the molecular features stabilizing the higher pH structures remain unclear. Here we...

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Publicado en:Nat Commun
Main Authors: Valéry, Céline, Deville-Foillard, Stéphanie, Lefebvre, Christelle, Taberner, Nuria, Legrand, Pierre, Meneau, Florian, Meriadec, Cristelle, Delvaux, Camille, Bizien, Thomas, Kasotakis, Emmanouil, Lopez-Iglesias, Carmen, Gall, Andrew, Bressanelli, Stéphane, Le Du, Marie-Hélène, Paternostre, Maïté, Artzner, Franck
Formato: Artigo
Idioma:Inglês
Publicado: Nature Pub. Group 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518280/
https://ncbi.nlm.nih.gov/pubmed/26190377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8771
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