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Identification of specific histidines as pH sensors in flavivirus membrane fusion

The flavivirus membrane fusion machinery, like that of many other enveloped viruses, is triggered by the acidic pH in endosomes after virus uptake by receptor-mediated endocytosis. It has been hypothesized that conserved histidines in the class II fusion protein E of these viruses function as molecu...

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Bibliografiska uppgifter
Huvudupphovsmän: Fritz, Richard, Stiasny, Karin, Heinz, Franz X.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568029/
https://ncbi.nlm.nih.gov/pubmed/18936253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806081
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