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Identification of specific histidines as pH sensors in flavivirus membrane fusion

The flavivirus membrane fusion machinery, like that of many other enveloped viruses, is triggered by the acidic pH in endosomes after virus uptake by receptor-mediated endocytosis. It has been hypothesized that conserved histidines in the class II fusion protein E of these viruses function as molecu...

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Detalles Bibliográficos
Main Authors: Fritz, Richard, Stiasny, Karin, Heinz, Franz X.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568029/
https://ncbi.nlm.nih.gov/pubmed/18936253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806081
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