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Identification of specific histidines as pH sensors in flavivirus membrane fusion

The flavivirus membrane fusion machinery, like that of many other enveloped viruses, is triggered by the acidic pH in endosomes after virus uptake by receptor-mediated endocytosis. It has been hypothesized that conserved histidines in the class II fusion protein E of these viruses function as molecu...

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Détails bibliographiques
Auteurs principaux: Fritz, Richard, Stiasny, Karin, Heinz, Franz X.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568029/
https://ncbi.nlm.nih.gov/pubmed/18936253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806081
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