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Mutational Analysis of the Zippering Reaction during Flavivirus Membrane Fusion

The current model of flavivirus membrane fusion is based on atomic structures of truncated forms of the viral fusion protein E in its dimeric prefusion and trimeric postfusion conformations. These structures lack the two transmembrane domains (TMDs) of E as well as the so-called stem, believed to be...

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Detalhes bibliográficos
Main Authors: Pangerl, Karen, Heinz, Franz X., Stiasny, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165785/
https://ncbi.nlm.nih.gov/pubmed/21697495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05129-11
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