Atomic view of the histidine environment stabilizing higher-pH conformations of pH-dependent proteins

External stimuli are powerful tools that naturally control protein assemblies and functions. For example, during viral entry and exit changes in pH are known to trigger large protein conformational changes. However, the molecular features stabilizing the higher pH structures remain unclear. Here we...

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Опубликовано в: :Nat Commun
Главные авторы: Valéry, Céline, Deville-Foillard, Stéphanie, Lefebvre, Christelle, Taberner, Nuria, Legrand, Pierre, Meneau, Florian, Meriadec, Cristelle, Delvaux, Camille, Bizien, Thomas, Kasotakis, Emmanouil, Lopez-Iglesias, Carmen, Gall, Andrew, Bressanelli, Stéphane, Le Du, Marie-Hélène, Paternostre, Maïté, Artzner, Franck
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Pub. Group 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518280/
https://ncbi.nlm.nih.gov/pubmed/26190377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8771
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