Atomic view of the histidine environment stabilizing higher-pH conformations of pH-dependent proteins

External stimuli are powerful tools that naturally control protein assemblies and functions. For example, during viral entry and exit changes in pH are known to trigger large protein conformational changes. However, the molecular features stabilizing the higher pH structures remain unclear. Here we...

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Published in:Nat Commun
Main Authors: Valéry, Céline, Deville-Foillard, Stéphanie, Lefebvre, Christelle, Taberner, Nuria, Legrand, Pierre, Meneau, Florian, Meriadec, Cristelle, Delvaux, Camille, Bizien, Thomas, Kasotakis, Emmanouil, Lopez-Iglesias, Carmen, Gall, Andrew, Bressanelli, Stéphane, Le Du, Marie-Hélène, Paternostre, Maïté, Artzner, Franck
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518280/
https://ncbi.nlm.nih.gov/pubmed/26190377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8771
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