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Atomic view of the histidine environment stabilizing higher-pH conformations of pH-dependent proteins

External stimuli are powerful tools that naturally control protein assemblies and functions. For example, during viral entry and exit changes in pH are known to trigger large protein conformational changes. However, the molecular features stabilizing the higher pH structures remain unclear. Here we...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Valéry, Céline, Deville-Foillard, Stéphanie, Lefebvre, Christelle, Taberner, Nuria, Legrand, Pierre, Meneau, Florian, Meriadec, Cristelle, Delvaux, Camille, Bizien, Thomas, Kasotakis, Emmanouil, Lopez-Iglesias, Carmen, Gall, Andrew, Bressanelli, Stéphane, Le Du, Marie-Hélène, Paternostre, Maïté, Artzner, Franck
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518280/
https://ncbi.nlm.nih.gov/pubmed/26190377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8771
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