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Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly

The rod of sarcomeric myosins directs thick filament assembly and is characterized by the insertion of four skip residues that introduce discontinuities in the coiled-coil heptad repeats. We report here that the regions surrounding the first three skip residues share high structural similarity despi...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Taylor, Keenan C., Buvoli, Massimo, Korkmaz, Elif Nihal, Buvoli, Ada, Zheng, Yuqing, Heinze, Nathan T., Cui, Qiang, Leinwand, Leslie A., Rayment, Ivan
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517226/
https://ncbi.nlm.nih.gov/pubmed/26150528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505813112
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