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Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly

The rod of sarcomeric myosins directs thick filament assembly and is characterized by the insertion of four skip residues that introduce discontinuities in the coiled-coil heptad repeats. We report here that the regions surrounding the first three skip residues share high structural similarity despi...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Taylor, Keenan C., Buvoli, Massimo, Korkmaz, Elif Nihal, Buvoli, Ada, Zheng, Yuqing, Heinze, Nathan T., Cui, Qiang, Leinwand, Leslie A., Rayment, Ivan
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517226/
https://ncbi.nlm.nih.gov/pubmed/26150528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505813112
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