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Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly

The rod of sarcomeric myosins directs thick filament assembly and is characterized by the insertion of four skip residues that introduce discontinuities in the coiled-coil heptad repeats. We report here that the regions surrounding the first three skip residues share high structural similarity despi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Taylor, Keenan C., Buvoli, Massimo, Korkmaz, Elif Nihal, Buvoli, Ada, Zheng, Yuqing, Heinze, Nathan T., Cui, Qiang, Leinwand, Leslie A., Rayment, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517226/
https://ncbi.nlm.nih.gov/pubmed/26150528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505813112
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