Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly

The rod of sarcomeric myosins directs thick filament assembly and is characterized by the insertion of four skip residues that introduce discontinuities in the coiled-coil heptad repeats. We report here that the regions surrounding the first three skip residues share high structural similarity despi...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Taylor, Keenan C., Buvoli, Massimo, Korkmaz, Elif Nihal, Buvoli, Ada, Zheng, Yuqing, Heinze, Nathan T., Cui, Qiang, Leinwand, Leslie A., Rayment, Ivan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517226/
https://ncbi.nlm.nih.gov/pubmed/26150528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505813112
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