Synthetic RNAs Mimicking Structural Domains in the Foot-and-Mouth Disease Virus Genome Elicit a Broad Innate Immune Response in Porcine Cells Triggered by RIG-I and TLR Activation

The innate immune system is the first line of defense against viral infections. Exploiting innate responses for antiviral, therapeutic and vaccine adjuvation strategies is being extensively explored. We have previously described, the ability of small in vitro RNA transcripts, mimicking the sequence...

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Bibliographic Details
Published in:Viruses
Main Authors: Borrego, Belén, Rodríguez-Pulido, Miguel, Revilla, Concepción, Álvarez, Belén, Sobrino, Francisco, Domínguez, Javier, Sáiz, Margarita
Format: Artigo
Language:Inglês
Published: MDPI 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517136/
https://ncbi.nlm.nih.gov/pubmed/26193305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7072807
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