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Synthetic RNAs Mimicking Structural Domains in the Foot-and-Mouth Disease Virus Genome Elicit a Broad Innate Immune Response in Porcine Cells Triggered by RIG-I and TLR Activation

The innate immune system is the first line of defense against viral infections. Exploiting innate responses for antiviral, therapeutic and vaccine adjuvation strategies is being extensively explored. We have previously described, the ability of small in vitro RNA transcripts, mimicking the sequence...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Viruses
Prif Awduron: Borrego, Belén, Rodríguez-Pulido, Miguel, Revilla, Concepción, Álvarez, Belén, Sobrino, Francisco, Domínguez, Javier, Sáiz, Margarita
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517136/
https://ncbi.nlm.nih.gov/pubmed/26193305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7072807
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