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RNA Structural Domains in Noncoding Regions of the Foot-and-Mouth Disease Virus Genome Trigger Innate Immunity in Porcine Cells and Mice

The induction of type I interferons (alpha/beta interferon [IFN-α/β]) in response to viral infection is a crucial step leading to the antiviral state in the host. Viruses produce double-stranded RNA (dsDNA) during their replication cycle that is sensed as nonself by host cells through different rece...

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Detalhes bibliográficos
Main Authors: Rodríguez-Pulido, Miguel, Borrego, Belén, Sobrino, Francisco, Sáiz, Margarita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126542/
https://ncbi.nlm.nih.gov/pubmed/21525336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00599-11
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