Synthetic RNAs Mimicking Structural Domains in the Foot-and-Mouth Disease Virus Genome Elicit a Broad Innate Immune Response in Porcine Cells Triggered by RIG-I and TLR Activation

The innate immune system is the first line of defense against viral infections. Exploiting innate responses for antiviral, therapeutic and vaccine adjuvation strategies is being extensively explored. We have previously described, the ability of small in vitro RNA transcripts, mimicking the sequence...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Borrego, Belén, Rodríguez-Pulido, Miguel, Revilla, Concepción, Álvarez, Belén, Sobrino, Francisco, Domínguez, Javier, Sáiz, Margarita
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517136/
https://ncbi.nlm.nih.gov/pubmed/26193305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7072807
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