Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus

The RNA helicase LGP2 (Laboratory of Genetics and Physiology 2) is a non-signaling member of the retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), whose pivotal role on innate immune responses against RNA viruses is being increasingly uncovered. LGP2 is known to work in synergy with mela...

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Publicat a:PLoS Pathog
Autors principals: Rodríguez Pulido, Miguel, Sánchez-Aparicio, María Teresa, Martínez-Salas, Encarnación, García-Sastre, Adolfo, Sobrino, Francisco, Sáiz, Margarita
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042790/
https://ncbi.nlm.nih.gov/pubmed/29958302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007135
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