Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene

Pulmonary inflammation can contribute to the development of lung cancer in humans. We investigated whether pulmonary inflammation alters the genotoxicity of polycyclic aromatic hydrocarbons (PAHs) in the lungs of mice and what mechanisms are involved. To model nonallergic acute inflammation, mice we...

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Bibliografski detalji
Izdano u:Toxicol Sci
Glavni autori: Arlt, Volker M., Krais, Annette M., Godschalk, Roger W., Riffo-Vasquez, Yanira, Mrizova, Iveta, Roufosse, Candice A., Corbin, Charmaine, Shi, Quan, Frei, Eva, Stiborova, Marie, van Schooten, Frederik-Jan, Phillips, David H., Spina, Domenico
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Benzo[a]pyrene and Respiratory Tract DNA Damage
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517052/
https://ncbi.nlm.nih.gov/pubmed/25911668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv086
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