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Factor XI and Contact Activation as Targets for Antithrombotic Therapy

The most commonly used anticoagulants produce therapeutic antithrombotic effects either by inhibiting thrombin or factor Xa, or by lowering the plasma levels of the precursors of these key enzymes, prothrombin and factor X. These drugs do not distinguish between thrombin generation contributing to t...

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Dades bibliogràfiques
Publicat a:J Thromb Haemost
Autors principals: Gailani, David, Bane, Charles E., Gruber, Andras
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516614/
https://ncbi.nlm.nih.gov/pubmed/25976012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13005
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