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Factor XI and Contact Activation as Targets for Antithrombotic Therapy
The most commonly used anticoagulants produce therapeutic antithrombotic effects either by inhibiting thrombin or factor Xa, or by lowering the plasma levels of the precursors of these key enzymes, prothrombin and factor X. These drugs do not distinguish between thrombin generation contributing to t...
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| Veröffentlicht in: | J Thromb Haemost |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516614/ https://ncbi.nlm.nih.gov/pubmed/25976012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13005 |
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