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Factor XI and Contact Activation as Targets for Antithrombotic Therapy

The most commonly used anticoagulants produce therapeutic antithrombotic effects either by inhibiting thrombin or factor Xa, or by lowering the plasma levels of the precursors of these key enzymes, prothrombin and factor X. These drugs do not distinguish between thrombin generation contributing to t...

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Podrobná bibliografie
Vydáno v:J Thromb Haemost
Hlavní autoři: Gailani, David, Bane, Charles E., Gruber, Andras
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516614/
https://ncbi.nlm.nih.gov/pubmed/25976012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13005
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