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Factor XI as a Therapeutic Target

Factor XIa is a plasma serine protease that contributes to thrombin generation primarily through proteolytic activation of factor IX. Traditionally considered part of the intrinsic pathway of coagulation, several lines of evidence now suggest that factor XIa serves as an interface between the vitami...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Gailani, David, Gruber, Andras
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919154/
https://ncbi.nlm.nih.gov/pubmed/27174099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.306925
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