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Plasma Contact Factors as Therapeutic Targets

Direct Oral Anticoagulants (DOACs) are small molecule inhibitors of the coagulation proteases thrombin and factor Xa that demonstrate comparable efficacy to warfarin for several common indications, while causing less serious bleeding. However, because their targets are required for the normal host-r...

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Detalhes bibliográficos
Publicado no:Blood Rev
Main Authors: Tillman, Benjamin F., Gruber, Andras, McCarty, Owen J. T., Gailani, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185818/
https://ncbi.nlm.nih.gov/pubmed/30075986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.blre.2018.04.001
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