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Factor XI as a target for antithrombotic therapy

Anticoagulants currently used in clinical practice to treat thromboembolic disorders are effective but increase the risk of severe bleeding because they target proteins that are essential for normal coagulation (hemostasis). Drugs with better safety profiles are required for prevention and treatment...

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Detalhes bibliográficos
Main Authors: Bane, Charles E., Gailani, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167190/
https://ncbi.nlm.nih.gov/pubmed/24886766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.05.018
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