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AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells

The role of autophagy in cisplatin anticancer action was investigated using human U251 glioma, rat C6 glioma and mouse L929 fibrosarcoma cell lines. A dose- and time-dependent induction of autophagy was observed in tumour cells following cisplatin treatment, as demonstrated by up-regulation of autop...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Harhaji-Trajkovic, L, Vilimanovich, U, Kravic-Stevovic, T, Bumbasirevic, V, Trajkovic, V
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516513/
https://ncbi.nlm.nih.gov/pubmed/20196784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00663.x
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