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Ginsenoside Rb3 provides protective effects against cisplatin‐induced nephrotoxicity via regulation of AMPK‐/mTOR‐mediated autophagy and inhibition of apoptosis in vitro and in vivo

OBJECTIVES: Based on previous reports that ginsenosides have been shown to exert better preventive effects on cisplatin‐induced kidney injury, the present work aims to evaluate the protective effects of ginsenoside Rb3 (G‐Rb3) on cisplatin‐induced renal damage and underlying mechanisms in vivo and i...

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Vydáno v:Cell Prolif
Hlavní autoři: Xing, Jing‐jing, Hou, Jin‐gang, Ma, Zhi‐na, Wang, Zi, Ren, Shen, Wang, Ying‐ping, Liu, Wen‐cong, Chen, Chen, Li, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668974/
https://ncbi.nlm.nih.gov/pubmed/31094028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12627
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