AMPK/mTOR Signaling in Autophagy Regulation During Cisplatin-Induced Acute Kidney Injury

Autophagy is a conserved, multistep pathway that degrades and recycles dysfunctional organelles and macromolecules to maintain cellular homeostasis. Mammalian target of rapamycin (mTOR) and adenosine-monophosphate activated-protein kinase (AMPK) are major negative and positive regulators of autophag...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: Wang, Ying, Liu, Zhiwen, Shu, Shaoqun, Cai, Juan, Tang, Chengyuan, Dong, Zheng
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773913/
https://ncbi.nlm.nih.gov/pubmed/33391038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.619730
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