Autophagy facilitates lung adenocarcinoma resistance to cisplatin treatment by activation of AMPK/mTOR signaling pathway

Resistance to cisplatin-based therapy is a major challenge in the control of lung cancer progression. However, the underlying mechanisms remain largely unclear. Autophagy is closely associated with resistance to lung cancer therapy, but the function of autophagy in cisplatin treatment is still contr...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Wu, Tao, Wang, Min-Cong, Jing, Li, Liu, Zhi-Yan, Guo, Hui, Liu, Ying, Bai, Yi-Yang, Cheng, Yang-Zi, Nan, Ke-Jun, Liang, Xuan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686226/
https://ncbi.nlm.nih.gov/pubmed/26715839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S95606
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