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Autophagy facilitates lung adenocarcinoma resistance to cisplatin treatment by activation of AMPK/mTOR signaling pathway

Resistance to cisplatin-based therapy is a major challenge in the control of lung cancer progression. However, the underlying mechanisms remain largely unclear. Autophagy is closely associated with resistance to lung cancer therapy, but the function of autophagy in cisplatin treatment is still contr...

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Библиографические подробности
Опубликовано в: :Drug Des Devel Ther
Главные авторы: Wu, Tao, Wang, Min-Cong, Jing, Li, Liu, Zhi-Yan, Guo, Hui, Liu, Ying, Bai, Yi-Yang, Cheng, Yang-Zi, Nan, Ke-Jun, Liang, Xuan
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686226/
https://ncbi.nlm.nih.gov/pubmed/26715839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S95606
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