SIRT3 Protects Against Acute Kidney Injury via AMPK/mTOR-Regulated Autophagy

Acute kidney injury (AKI), which involves the loss of kidney function caused by damage to renal tubular cells, is an important public health concern. We previously showed that sirtuin (SIRT)3 protects the kidneys against mitochondrial damage by inhibiting the nucleotide-binding domain (NOD)-like rec...

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Dettagli Bibliografici
Pubblicato in:Front Physiol
Autori principali: Zhao, Wenyu, Zhang, Lei, Chen, Rui, Lu, Hanlan, Sui, Mingxing, Zhu, Youhua, Zeng, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246697/
https://ncbi.nlm.nih.gov/pubmed/30487750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01526
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