Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy

During intracellular infections, autophagy significantly contributes to the elimination of pathogens, regulation of pro-inflammatory signaling, secretion of immune mediators and in coordinating the adaptive immune system. Intracellular pathogens such as S. Typhimurium have evolved mechanisms to circ...

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Vydáno v:PLoS Pathog
Hlavní autoři: Ganesan, Raja, Hos, Nina Judith, Gutierrez, Saray, Fischer, Julia, Stepek, Joanna Magdalena, Daglidu, Evmorphia, Krönke, Martin, Robinson, Nirmal
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325604/
https://ncbi.nlm.nih.gov/pubmed/28192515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006227
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