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Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy
During intracellular infections, autophagy significantly contributes to the elimination of pathogens, regulation of pro-inflammatory signaling, secretion of immune mediators and in coordinating the adaptive immune system. Intracellular pathogens such as S. Typhimurium have evolved mechanisms to circ...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5325604/ https://ncbi.nlm.nih.gov/pubmed/28192515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006227 |
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