Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy

During intracellular infections, autophagy significantly contributes to the elimination of pathogens, regulation of pro-inflammatory signaling, secretion of immune mediators and in coordinating the adaptive immune system. Intracellular pathogens such as S. Typhimurium have evolved mechanisms to circ...

Full description

Saved in:
Bibliographic Details
Published in:PLoS Pathog
Main Authors: Ganesan, Raja, Hos, Nina Judith, Gutierrez, Saray, Fischer, Julia, Stepek, Joanna Magdalena, Daglidu, Evmorphia, Krönke, Martin, Robinson, Nirmal
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325604/
https://ncbi.nlm.nih.gov/pubmed/28192515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006227
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items