Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin

The sphingolipid metabolising enzyme Acid Sphingomyelinase (A-SMase) has been recently shown to inhibit melanoma progression and correlate inversely to tumour grade. In this study we have investigated the role of A-SMase in the chemo-resistance to anticancer treatmentusing mice with melanoma allogra...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cervia, Davide, Assi, Emma, De Palma, Clara, Giovarelli, Matteo, Bizzozero, Laura, Pambianco, Sarah, Di Renzo, Ilaria, Zecchini, Silvia, Moscheni, Claudia, Vantaggiato, Chiara, Procacci, Patrizia, Clementi, Emilio, Perrotta, Cristiana
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Autophagy and Cell Death
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041885/
https://ncbi.nlm.nih.gov/pubmed/27107419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8735
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