Acid Sphingomyelinase Downregulation Enhances Mitochondrial Fusion and Promotes Oxidative Metabolism in a Mouse Model of Melanoma

Melanoma is the most severe type of skin cancer. Its unique and heterogeneous metabolism, relying on both glycolysis and oxidative phosphorylation, allows it to adapt to disparate conditions. Mitochondrial function is strictly interconnected with mitochondrial dynamics and both are fundamental in tu...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Coazzoli, Marco, Napoli, Alessandra, Roux-Biejat, Paulina, De Palma, Clara, Moscheni, Claudia, Catalani, Elisabetta, Zecchini, Silvia, Conte, Vincenzo, Giovarelli, Matteo, Caccia, Sonia, Procacci, Patrizia, Cervia, Davide, Clementi, Emilio, Perrotta, Cristiana
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226741/
https://ncbi.nlm.nih.gov/pubmed/32244541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040848
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