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Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined (13)C Hyperpolarized Magnetic Resonance and Echocardiography Study
Although diabetic cardiomyopathy is widely recognised, there are no specific treatments available. Altered myocardial substrate selection has emerged as a candidate mechanism behind the development of cardiac dysfunction in diabetes. As pyruvate dehydrogenase (PDH) activity appears central to the ba...
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| Publié dans: | Diabetes |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516266/ https://ncbi.nlm.nih.gov/pubmed/25795215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1560 |
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