Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined (13)C Hyperpolarized Magnetic Resonance and Echocardiography Study

Although diabetic cardiomyopathy is widely recognised, there are no specific treatments available. Altered myocardial substrate selection has emerged as a candidate mechanism behind the development of cardiac dysfunction in diabetes. As pyruvate dehydrogenase (PDH) activity appears central to the ba...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Diabetes
Prif Awduron: Le Page, Lydia M., Rider, Oliver J., Lewis, Andrew J., Ball, Vicky, Clarke, Kieran, Johansson, Edvin, Carr, Carolyn A., Heather, Lisa C., Tyler, Damian J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516266/
https://ncbi.nlm.nih.gov/pubmed/25795215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1560
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