A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors

BACKGROUND: Dysregulation of microRNA (miRNA) has been implicated in gastrointestinal stromal tumors (GISTs) but the mechanism is not fully understood. In this study, we aimed to explore the involvement of epigenetic alteration of miRNA genes in GISTs. METHODS: GIST-T1 cells were treated with 5-aza-...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Isosaka, Mai, Niinuma, Takeshi, Nojima, Masanori, Kai, Masahiro, Yamamoto, Eiichiro, Maruyama, Reo, Nobuoka, Takayuki, Nishida, Toshirou, Kanda, Tatsuo, Taguchi, Takahiro, Hasegawa, Tadashi, Tokino, Takashi, Hirata, Koichi, Suzuki, Hiromu, Shinomura, Yasuhisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516245/
https://ncbi.nlm.nih.gov/pubmed/26214687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133754
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