A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors

BACKGROUND: Dysregulation of microRNA (miRNA) has been implicated in gastrointestinal stromal tumors (GISTs) but the mechanism is not fully understood. In this study, we aimed to explore the involvement of epigenetic alteration of miRNA genes in GISTs. METHODS: GIST-T1 cells were treated with 5-aza-...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Isosaka, Mai, Niinuma, Takeshi, Nojima, Masanori, Kai, Masahiro, Yamamoto, Eiichiro, Maruyama, Reo, Nobuoka, Takayuki, Nishida, Toshirou, Kanda, Tatsuo, Taguchi, Takahiro, Hasegawa, Tadashi, Tokino, Takashi, Hirata, Koichi, Suzuki, Hiromu, Shinomura, Yasuhisa
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516245/
https://ncbi.nlm.nih.gov/pubmed/26214687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133754
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