A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors

BACKGROUND: Dysregulation of microRNA (miRNA) has been implicated in gastrointestinal stromal tumors (GISTs) but the mechanism is not fully understood. In this study, we aimed to explore the involvement of epigenetic alteration of miRNA genes in GISTs. METHODS: GIST-T1 cells were treated with 5-aza-...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Isosaka, Mai, Niinuma, Takeshi, Nojima, Masanori, Kai, Masahiro, Yamamoto, Eiichiro, Maruyama, Reo, Nobuoka, Takayuki, Nishida, Toshirou, Kanda, Tatsuo, Taguchi, Takahiro, Hasegawa, Tadashi, Tokino, Takashi, Hirata, Koichi, Suzuki, Hiromu, Shinomura, Yasuhisa
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516245/
https://ncbi.nlm.nih.gov/pubmed/26214687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133754
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