A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors

BACKGROUND: Dysregulation of microRNA (miRNA) has been implicated in gastrointestinal stromal tumors (GISTs) but the mechanism is not fully understood. In this study, we aimed to explore the involvement of epigenetic alteration of miRNA genes in GISTs. METHODS: GIST-T1 cells were treated with 5-aza-...

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Publicat a:PLoS One
Autors principals: Isosaka, Mai, Niinuma, Takeshi, Nojima, Masanori, Kai, Masahiro, Yamamoto, Eiichiro, Maruyama, Reo, Nobuoka, Takayuki, Nishida, Toshirou, Kanda, Tatsuo, Taguchi, Takahiro, Hasegawa, Tadashi, Tokino, Takashi, Hirata, Koichi, Suzuki, Hiromu, Shinomura, Yasuhisa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516245/
https://ncbi.nlm.nih.gov/pubmed/26214687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133754
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