A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors

BACKGROUND: Dysregulation of microRNA (miRNA) has been implicated in gastrointestinal stromal tumors (GISTs) but the mechanism is not fully understood. In this study, we aimed to explore the involvement of epigenetic alteration of miRNA genes in GISTs. METHODS: GIST-T1 cells were treated with 5-aza-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Isosaka, Mai, Niinuma, Takeshi, Nojima, Masanori, Kai, Masahiro, Yamamoto, Eiichiro, Maruyama, Reo, Nobuoka, Takayuki, Nishida, Toshirou, Kanda, Tatsuo, Taguchi, Takahiro, Hasegawa, Tadashi, Tokino, Takashi, Hirata, Koichi, Suzuki, Hiromu, Shinomura, Yasuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516245/
https://ncbi.nlm.nih.gov/pubmed/26214687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133754
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