Attenuated Semliki Forest virus for cancer treatment in dogs: safety assessment in two laboratory Beagles

BACKGROUND: Dogs suffer from spontaneous tumors which may be amenable to therapies developed for human cancer patients, and dogs may serve as large-animal cancer models. A non-pathogenic Semliki Forest virus vector VA7-EGFP previously showed promise in targeting human tumor xenografts in mice, but t...

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Veröffentlicht in:BMC Vet Res
Hauptverfasser: Autio, Karoliina P. M., Ruotsalainen, Janne J., Anttila, Marjukka O., Niittykoski, Minna, Waris, Matti, Hemminki, Akseli, Vähä-Koskela, Markus J. V., Hinkkanen, Ari E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515883/
https://ncbi.nlm.nih.gov/pubmed/26215394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-015-0498-2
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