Resistance to Two Heterologous Neurotropic Oncolytic Viruses, Semliki Forest Virus and Vaccinia Virus, in Experimental Glioma

Attenuated Semliki Forest virus (SFV) may be suitable for targeting malignant glioma due to its natural neurotropism, but its replication in brain tumor cells may be restricted by innate antiviral defenses. We attempted to facilitate SFV replication in glioma cells by combining it with vaccinia viru...

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Autors principals: Vähä-Koskela, Markus J. V., Le Boeuf, Fabrice, Lemay, Chantal, De Silva, Naomi, Diallo, Jean-Simon, Cox, Julie, Becker, Michelle, Choi, Youngmin, Ananth, Abhirami, Sellers, Clara, Breton, Sophie, Roy, Dominic, Falls, Theresa, Brun, Jan, Hemminki, Akseli, Hinkkanen, Ari, Bell, John C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571476/
https://ncbi.nlm.nih.gov/pubmed/23221568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01609-12
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